DR. MARTA CLOS-SANSALVADOR. (Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP). Badalona, Spain).

10:00-10:30 Isolation of Extracellular Vesicles. DR. FRANCESC E. BORRÀS & MARTA SANROQUE-MUÑÓZ. (Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP). Badalona, Spain).

10:30-11:00 EV uptake and functional assays. DR. MARÍA YAÑEZ-MO & MIGUEL PALMA-COBO.

11:30-11:45 EV cargo preparation for OMICS analysis. DR. ROCIO BRAVO-MIANA. (IIS Biogipuzkoa, San Sebastian, Spain).

11:45-12:00 Single-vesicle phenotyping. DR. ANA TALAMILLO. (CIC bioGUNE-BRTA. Bilbao, Spain).

12:00-12:30 Extracellular Vesicles in Therapy. DR. CLARA I. RODRÍGUEZ & LEIRE CABODEVILLA. (Biobizkaia Health Research Institute, Bilbao, Spain).

12:30-13:00 Extracellular Vesicles as Diagnostic Tool. DR. DAVID OTAEGI & JONE ARIZAGA. (IIS Biogipuzkoa, San Sebastian, Spain).

MARCEL-LA FRANQUESA BARTOLOME. (Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain. President of GEIVEX) and JUANMA FALCÓN-PÉREZ (CIC bioGUNE-BRTA, CIBERehd, IKERBASQUE Research Foundation, Bilbao, Spain. Chair of Local Organizing Committee).

CHAIR: DR. AINTZANE APRAIZ (University of the Basque Country (UPV/EHU), Bilbao, Spain).

9:00 Keynote Lecture “Navigating Complexity in Extracellular Vesicle Research”. PROF. EDIT BUZAS (Department of Genetics, Cell and Immunobiology at Semmelweis University, Budapest, Hungary).

9:45 Selected talk on Biology of Extracellular Vesicles.

CHAIR: DR. EDORTA SANTOS (University of the Basque Country (EHU), Vitoria, Spain).

10:00 Sponsor Talk 1.

10:15 Sponsor Talk 2.

CHAIR & MODERATOR: DR. JOAQUIM VIVES (Cell Therapy Service Blood and Tissue Bank, Barcelona, Spain)

11:30 “Introduction EUROPEAN NETWORK OF SoHO ESTABLISHMENTS FOR RAPID AND SUSTAINABLE ACCESS TO ATMPs (BTCs4ATMP)”. DR. JOAQUIM VIVES (Cell Therapy Service Blood and Tissue Bank, Barcelona, Spain).

11:40 “The European ecosystem to foster therapeutics”. DR. SOL RUIZ (Head of Biologics, Biotechnology and Advanced Therapies at the Spanish Medicines Agency (AEMPS). Madrid, Spain).

12:15 “A path to a phase-1 ready EV manufacturing process”. DR. CHANTAL MARTIN (Co-founder and Managing Director, Product Development for Capital BioVentures / Founder and Principal Consultant for CMConsulting Inc. Otawa, Canada).

12:50 Selected talk on Therapeutics applications of Extracellular Vesicles.

13:00 Discussion moderated by DR. VIVES.

CHAIRS: DR. PATRICIA ASPICHUETA (University of the Basque Country (UPV/EHU), Biobizkaia Health Research Institute and CIBERehd. Bilbao, Spain), MARC LIEBANA JORDAN (CIC bioGUNE-BRTA, Bilbao, Spain).

14:30 Focus Lecture. “The challenges of Isolation and characterization of Extracellular Vesicles”. JAVIER MUÑOZ PERALTA (Biobizkaia Health Research Institute, Bilbao, Spain).

15:00 Selected talk on EV Isolation.

15:10 Selected talk on EV Characterization.

15:20 Selected talk on EV Activity.

CHAIR: DR. SANDRA SOUKUP (Achucarro Basque Center for Neuroscience, Ikerbasque Foundation for Science, Bilbao, Spain).

15:30 Sponsor Talk 3.

15:45 Sponsor Talk 4.

CHAIR: DR. MARÍA YAÑEZ-MO (Centro de Biología Molecular Severo Ochoa (CBM-SO), Universidad Autónoma de Madrid. Spain).

CHAIR: DR. ROSA HERNANDEZ (University of the Basque Country (UPV/EHU). Vitoria, Spain).

9:00 Keynote Lecture. “Extracellular vesicles as vectors for selective delivery of therapeutic nanoparticles to tumors”. PROF. JESUS SANTAMARIA (Institute of Nanoscience and Materials of Aragón (INMA), CSIC–University of Zaragoza. Department of Chemical and Environmental Engineering, University of Zaragoza. Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN). Zaragoza, Spain).

9:45 Selected talk on Application of Extracellular Vesicles.

CHAIR: DR. DAVID GIL (Basque Resource for Electron Microscopy (BREM cryo-EM Facility), Instituto Biofisika (EHU-CSIC), Bilbao, Spain).

10:00 Sponsor Talk 5.

10:15 Sponsor Talk 6.

CHAIRS: DR. LEYRE URIGÜEN ECHEVARRIA (University of the Basque Country (UPV/EHU)/Biomedical Research Centre in Mental Health Network (CIBERSAM). Bilbao, Spain) and DR. ALFREDO RAMOS-MIGUEL (University of the Basque Country (UPV/EHU). Bilbao, Spain).

11:15 Selected talk on EV Neurobiology I.

11:30 Selected talk on EV Neurobiology II.

11:45 Selected talk on EV Neurodegeneration I.

12:00 Selected talk on EV Neurodegeneration II.

12:15 Selected talk on EV Neurological disease III.

CHAIR: DR. UXIA GURRIARAN (CIC bioGUNE-BRTA, Bilbao, Spain).

12:30 Sponsor Talk 7.

12:45 Sponsor Talk 8.

CHAIRS: DR. VERONICA TORRANO (University of the Basque Country (UPV/EHU), Bilbao, Spain) and ENRIQUE BASTÓN DE LA FUENTE (CNIO, Madrid, Spain).

14:30 Invited Lecture. “Extracellular vesicles as tools for cancer immunotherapy”. PROF. SUSANNE GABRIELSSON (Division of Immunology and Respiratory Medicine, Department of Medicine, Karolinska Institute, Solna, Sweden).

15:10 Selected talk on EV cancer progression.

15:20 Selected talk on EV tumour environment

15:30 Selected talk on EV cancer metastasis.

CHAIR: DR. ROCIO BRAVO MIANA (IIS Biogipuzkoa, San Sebastian, Spain).

15:45 Sponsor Talk 9.

16:00 Sponsor Talk 10.

CHAIR: DR. MARIA PARDO (Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain).

CHAIR: DR. HERNANDO DEL PORTILLO (Barcelona Institute for Global Health (ISGlobal). Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP). Badalona, Spain).

9:15 Focus Lecture. “Extracellular Vesicles in Human Interactions with Bacteria and Other Pathogens”. DR. JAVIER SOTILLO (Parasitology Reference and Research Laboratory, National Center for Microbiology, Instituto Salud Carlos III, Madrid, Spain).

9:45 Selected talk on EV human-pathogen communication.

9:55 Selected talk on Bacterial EVs.

10:05 Selected talk on EV infectious disease.

CHAIR: DR. MARTA CLOS-SANSALVADOR (Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP). Badalona, Spain).

10:15 Sponsor Talk 11.

10:25 Sponsor Talk 12.